Background
The Finnish Geriatric Intervention Study to Prevent Cognitive Impairment and Disability (FINGER) showed a positive effect after a 2-year intervention targeting several lifestyles and vascular risk factors simultaneously. LETHE will go beyond and provide a data-driven risk factor prediction model for older individuals at risk of cognitive decline building upon big data analysis of cross-sectional observational and longitudinal intervention datasets from 4 clinical centers in Europe including the 11-years analysis of FINGER. LETHE will establish novel digital biomarkers, for early detection of risk factors, based on unobtrusive ICT-based passive and active monitoring.
Aim
The aim is to establish a digital-enabled intervention for cognitive decline prevention based on the evolution of a successful protocol (FINGER) evolving into an ICT-based preventive lifestyle intervention through individualized profiling, personalized recommendations, feedback and support (FINGER 2.0) – well targeted on a population stratified by cost-effective biological biomarkers. The LETHE solution will be tested in a feasibility study validating the achieved improvements.
Project Start
The project’s official start took place on January 25th and 26th 2021 in form of an online kick-off meeting chaired by project coordinator Sten Hanke. The meeting provided a platform for all partner organization to introduce themselves and to establish first collaborations and concluded with a general assembly assessing the project’s main challenges.
